Related Party Transactions - Additional Information (Details) - USD ($)	12 Months Ended
Dec. 31, 2022	Dec. 31, 2021
Related Party Transaction [Line Items]
Stock-based compensation expense related to options granted	$ 16,618,000	$ 29,853,000
Incremental stock-based compensation expense	2,115,000
General and Administrative Expense
Related Party Transaction [Line Items]
Stock-based compensation expense related to options granted	10,225,000	14,792,000
Severance Costs	1,297,750
Research and Development Expense
Related Party Transaction [Line Items]
Stock-based compensation expense related to options granted	6,393,000	15,061,000
Severance Costs	$ 1,020,000
Purdue Research Foundation [Member]
Related Party Transaction [Line Items]
Shares held by related party	154,497
Related party expenses	$ 195,000	0
Restricted Stock Units (RSUs)
Related Party Transaction [Line Items]
Stock-based compensation expense related to options granted	1,337,000,000	$ 0
Maximum \| Purdue Research Foundation [Member]
Related Party Transaction [Line Items]
Contractual Obligation	$ 4,250,000

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)(i)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

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Costs of sales and operating expenses for the period incurred from transactions with related parties.

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 220
-SubTopic 10
-Section S99
-Paragraph 2
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Amount of expenses for special or contractual termination benefits provided to current employees involuntarily terminated under a benefit arrangement associated exit or disposal activities pursuant to an authorized plan. Excludes expenses related to one-time termination benefits, a discontinued operation or an asset retirement obligation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 28
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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(2)(iii)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

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