Leases - Additional Information (Details) - USD ($)	1 Months Ended						6 Months Ended	12 Months Ended
	Oct. 31, 2022	Mar. 31, 2022	Jul. 31, 2021	May 31, 2020	May 31, 2019	Jun. 30, 2018	Jun. 30, 2022	Dec. 31, 2022	Dec. 31, 2021	May 31, 2021	May 13, 2019
Lessee Lease Description [Line Items]
Renewal options					false
Operating lease payments			$ 1,300,000		$ 0	$ 0
Repurchase option percentage						100.00%
Operating leases period						3 years
Operating lease payments paid for additional space					$ 63,000
Operating lease termination month and year				2021-07	2021-07
Operating lease liability				$ 172,000	$ 0			$ 377,000	$ 1,161,000
Operating lease asset			$ 44,000,000	$ 172,000				291,000	1,165,000	$ 1,200,000
Future rent expense								$ 318,000,000
Finance lease amortized period on equipment service								18 months
Finance lease amortization of right of use assets								$ 50,000	220,000
Operating lease renewal		1 year
Right-of-use assets obtained in exchange for new operating lease liabilities		$ 640,000,000
Impairment charges									$ 0
Minimum
Lessee Lease Description [Line Items]
Finance lease amortized period on equipment service									20 months
Maximum
Lessee Lease Description [Line Items]
Operating lease remaining term on a straight-line basis								12 months
Finance lease amortized period on equipment service									34 months
San Diego, California
Lessee Lease Description [Line Items]
Lease agreement period				3 years
Operating lease payments				$ 337,000
Impairment charges								$ 136,000	$ 0
San Diego, California | Prepaid Expenses and Other Current Assets
Lessee Lease Description [Line Items]
Security deposit paid								29,000
South San Francisco
Lessee Lease Description [Line Items]
Operating lease payments							$ 271,000,000
Operating lease liability							256,000
Security deposit paid							$ 17,000,000
West Lafayette
Lessee Lease Description [Line Items]
Lease agreement period	15 months
Operating lease payments	$ 151,000,000
Operating lease liability	$ 145,000
Right-of-use assets obtained in exchange for new operating lease liabilities								$ 10,000
Series B Redeemable Convertible Preferred Stock
Lessee Lease Description [Line Items]
Lease agreement period						3 years
Renewal options						false
Shares issued						114,437
Convertible preferred stock, fair value						$ 1,100,000
Series B Redeemable Convertible Preferred Stock | IPO
Lessee Lease Description [Line Items]
Conversion of redeemable convertible preferred stock to common stock ratio											100.00%