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Equity Incentive Plans - Summary of Weighted Average Assumptions to Calculate the Fair Value of Stock-Based Compensation (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected dividend yield 0.00%    
Service Based Stock Options      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected volatility 87.56% 86.69% 80.19%
Expected dividend yield 0.00% 0.00% 0.00%
Expected term (in years) 6 years 2 months 23 days 6 years 2 months 23 days 6 years 3 months
Risk-free interest rate 1.15% 0.80% 1.90%
Market Based Performance Stock Options      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected volatility   95.00%  
Expected term (in years)   10 years  
Risk-free interest rate   0.90%