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Equity Incentive Plans - Summary of Employee and Non-Employee Stock-Based Compensation Expense (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total stock-based compensation $ 29,853 $ 14,470 $ 2,056
General and Administrative Expense      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total stock-based compensation 14,792 7,441 1,378
Research and Development Expense      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total stock-based compensation $ 15,061 $ 7,029 $ 678