Collaboration and license agreements - Schedule of financial information related to collaboration and license agreements (Details) - USD ($) $ in Thousands	Mar. 31, 2026	Dec. 31, 2025
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	$ 2,883	$ 2,401
Deferred revenue, current	10,124	12,493
Deferred revenue, net of current	15,440	15,841
Deferred revenue, total	25,564	28,334
MKDG Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	883	1,892
Deferred revenue, current	3,034	3,913
Deferred revenue, net of current	0	0
Deferred revenue, total	3,034	3,913
Betta Agreements
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	0	9
Deferred revenue, current	704	531
Deferred revenue, net of current	14,014	14,194
Deferred revenue, total	14,718	14,725
Roche Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	0	500
Deferred revenue, current	6,386	8,049
Deferred revenue, net of current	1,426	1,647
Deferred revenue, total	7,812	$ 9,696
Biogen Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	2,000
Deferred revenue, current	0
Deferred revenue, net of current	0
Deferred revenue, total	$ 0