Property and equipment (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2026	Mar. 31, 2025	Dec. 31, 2025
Property Plant And Equipment [Line Items]
Property and equipment	$ 15,623		$ 15,521
Less: accumulated depreciation	(11,131)		(10,777)
Total property and equipment, net	4,492		4,744
Depreciation expense	360	$ 364
Laboratory equipment
Property Plant And Equipment [Line Items]
Property and equipment	8,861		8,819
Leasehold improvements
Property Plant And Equipment [Line Items]
Property and equipment	4,548		4,548
Furniture and fixtures
Property Plant And Equipment [Line Items]
Property and equipment	1,435		1,435
Office equipment
Property Plant And Equipment [Line Items]
Property and equipment	622		621
Computer equipment
Property Plant And Equipment [Line Items]
Property and equipment	$ 157		$ 98