Collaboration and license agreements - Schedule of financial information related to collaboration and license agreements (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	$ 2,401	$ 3,102
Deferred revenue, current	12,493	18,712
Deferred revenue, net of current	15,841	28,457
Deferred Revenue, Total	28,334	47,169
Merck, KGaA Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	1,892	2,064
Deferred revenue, current	3,913	5,396
Deferred revenue, net of current	0	7,977
Deferred Revenue, Total	3,913	13,373
Merck Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable		0
Deferred revenue, current		3,441
Deferred revenue, net of current		2,581
Deferred Revenue, Total		6,022
Betta Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	9	1,038
Deferred revenue, current	531	4,038
Deferred revenue, net of current	14,194	11,243
Deferred Revenue, Total	14,725	15,281
Roche Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	500	0
Deferred revenue, current	8,049	5,837
Deferred revenue, net of current	1,647	6,656
Deferred Revenue, Total	$ 9,696	$ 12,493