Collaboration and license agreements - Merck Agreement (Details) $ in Millions	1 Months Ended
	Jan. 31, 2024 USD ($)	Dec. 31, 2025 USD ($)	Dec. 11, 2023 performanceObligation	Dec. 31, 2018 performanceObligation
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of performance obligations | performanceObligation				12
Merck Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Upfront payment | $	$ 10.0
Number of performance obligations | performanceObligation			1
Estimated transaction price | $		$ 10.0