Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Income Statement [Abstract]
Revenue from collaboration agreements	$ 35,947	$ 35,584
Operating expenses:
Research and development	104,240	110,637
General and administrative	36,196	42,124
Impairment loss on right-of-use asset	10,733	0
Restructuring	0	2,437
Total operating expenses	151,169	155,198
Loss from operations	(115,222)	(119,614)
Other income (expense), net
Interest and other income, net	10,349	14,429
Total other income, net	10,349	14,429
Loss before income taxes	(104,873)	(105,185)
Income tax expense	(121)	(131)
Net loss	$ (104,994)	$ (105,316)
Net loss per share — basic (in dollars per share)	$ (1.27)	$ (1.52)
Net loss per share — diluted (in dollars per share)	$ (1.27)	$ (1.52)
Weighted-average number of shares - basic (in shares)	82,894,459	69,372,993
Weighted-average number of shares - diluted (in shares)	82,894,459	69,372,993
Other Comprehensive income (loss):
Unrealized (loss) gain on marketable securities	$ (3)	$ 180
Comprehensive loss	$ (104,997)	$ (105,136)
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]	Collaborative Arrangement [Member]	Collaborative Arrangement [Member]