Property and equipment - Summary of property and equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Property Plant And Equipment [Line Items]
Total property and equipment	$ 15,521	$ 15,078
Less: accumulated depreciation	(10,777)	(9,236)
Total property and equipment, net	4,744	5,842
Laboratory equipment
Property Plant And Equipment [Line Items]
Total property and equipment	8,819	8,212
Leasehold improvements
Property Plant And Equipment [Line Items]
Total property and equipment	4,548	4,712
Furniture and fixtures
Property Plant And Equipment [Line Items]
Total property and equipment	1,435	1,435
Office equipment
Property Plant And Equipment [Line Items]
Total property and equipment	621	621
Computer equipment
Property Plant And Equipment [Line Items]
Total property and equipment	$ 98	$ 98