Nature of the business (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Net loss	$ 104,994	$ 105,316
Accumulated deficit	738,693	$ 633,699
Cash, cash equivalents and marketable securities	$ 297,100