Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Income Statement [Abstract]
Revenue from collaboration agreements	$ 11,230	$ 15,362	$ 24,931	$ 30,407
Operating expenses:
Research and development	25,989	31,838	79,258	78,124
General and administrative	8,920	11,768	27,017	31,751
Impairment of long-lived assets	10,733	0	10,733	0
Restructuring	0	0	0	2,437
Total operating expenses	45,642	43,606	117,008	112,312
Loss from operations	(34,412)	(28,244)	(92,077)	(81,905)
Other income, net:
Interest and other income, net	2,246	3,578	7,569	11,162
Total other income, net	2,246	3,578	7,569	11,162
Loss before income taxes	(32,166)	(24,666)	(84,508)	(70,743)
Net loss	$ (32,166)	$ (24,666)	$ (84,508)	$ (70,743)
Net loss per share − basic (in dollars per share)	$ (0.44)	$ (0.35)	$ (1.18)	$ (1.03)
Net loss per share − diluted (in dollars per share)	$ (0.44)	$ (0.35)	$ (1.18)	$ (1.03)
Weighted-average number of shares used in computed net loss per share − basic	72,563,311	69,627,190	71,473,704	68,958,938
Weighted-average number of shares used in computed net loss per share − diluted	72,563,311	69,627,190	71,473,704	68,958,938
Other comprehensive income (loss)
Unrealized gain on marketable securities	$ 117	$ 895	$ 87	$ 582
Comprehensive loss	$ (32,049)	$ (23,771)	$ (84,421)	$ (70,161)
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]			Collaborative Arrangement [Member]	Collaborative Arrangement [Member]