Segment reporting (Tables)

9 Months Ended

Sep. 30, 2025

Segment Reporting [Abstract]

Schedule of Segment Reporting Information, by Segment

The following tables presents selected financial information with respect to the Company’s single operating segment for the three and nine months ended September 30, 2025 and 2024.

(in thousands)	Three Months Ended September 30,				Nine Months Ended September 30,
	2025		2024		2025		2024
Revenue	$	—	$	—	$	—	$	—
Operating expenses:
Development expenses	12,885		18,407		40,040		41,053
Research expenses	8,253		8,048		24,823		22,855
General and administrative	9,178		8,320		26,320		24,540
Segment operating expenses	30,316		34,775		91,183		88,448
Reconciliation of profit or loss
Non-operating income	(2,246)		(3,578)		(7,569)		(11,162)
Adjustments or reconciling items(1)	4,096		(6,531)		894		(6,543)
Consolidated net loss	$	(32,166)	$	(24,666)	$	(84,508)	$	(70,743)

(1) The reconciling items include revenue, stock-based compensation expense, and impairment of long-lived assets expense for the three and nine months ended September 30, 2025 and the three months ended September 30, 2024. The

reconciling items include revenue, stock-based compensation expense, and restructuring expense for the nine months ended September 30, 2024.