Collaboration and license agreements - Schedule of financial information related to collaboration and license agreements (Details) - USD ($) $ in Thousands	Jun. 30, 2025	Dec. 31, 2024
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	$ 2,158	$ 3,102
Deferred revenue, current	22,620	18,712
Deferred revenue, net of current	21,150	28,457
Deferred revenue, total	43,770	47,169
MKDG Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	2,013	2,064
Deferred revenue, current	6,811	5,396
Deferred revenue, net of current	5,081	7,977
Deferred revenue, total	11,892	13,373
Merck Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	0	0
Deferred revenue, current	3,441	3,441
Deferred revenue, net of current	402	2,581
Deferred revenue, total	3,843	6,022
Betta Agreements
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	145	1,038
Deferred revenue, current	2,992	4,038
Deferred revenue, net of current	11,978	11,243
Deferred revenue, total	14,970	15,281
Roche Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	0	0
Deferred revenue, current	9,376	5,837
Deferred revenue, net of current	3,689	6,656
Deferred revenue, total	$ 13,065	$ 12,493