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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Income Statement [Abstract]        
Revenue from collaboration agreements $ 6,463 $ 12,006 $ 13,701 $ 15,045
Operating expenses:        
Research and development 26,197 23,753 53,269 46,286
General and administrative 8,767 9,695 18,097 19,983
Restructuring 0 0 0 2,437
Total operating expenses 34,964 33,448 71,366 68,706
Loss from operations (28,501) (21,442) (57,665) (53,661)
Other income, net:        
Interest and other income, net 2,481 3,726 5,323 7,584
Total other income, net 2,481 3,726 5,323 7,584
Loss before income taxes (26,020) (17,716) (52,342) (46,077)
Net loss $ (26,020) $ (17,716) $ (52,342) $ (46,077)
Net loss per share − basic (in dollars per share) $ (0.37) $ (0.26) $ (0.74) $ (0.67)
Net loss per share − diluted (in dollars per share) $ (0.37) $ (0.26) $ (0.74) $ (0.67)
Weighted-average number of shares used in computed net loss per share − basic 71,005,743 68,810,259 70,919,871 68,621,214
Weighted-average number of shares used in computed net loss per share − diluted 71,005,743 68,810,259 70,919,871 68,621,214
Other comprehensive income (loss)        
Unrealized loss on marketable securities $ (73) $ (60) $ (83) $ (313)
Comprehensive loss $ (26,093) $ (17,776) $ (52,425) $ (46,390)
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]     Collaborative Arrangement [Member] Collaborative Arrangement [Member]