Property and equipment (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024	Dec. 31, 2024
Property Plant And Equipment [Line Items]
Property and equipment	$ 15,557		$ 15,557		$ 15,078
Less: accumulated depreciation	(10,017)		(10,017)		(9,236)
Total property and equipment, net	5,540		5,540		5,842
Depreciation expense	416	$ 296	780	$ 744
Laboratory equipment
Property Plant And Equipment [Line Items]
Property and equipment	8,691		8,691		8,212
Leasehold improvements
Property Plant And Equipment [Line Items]
Property and equipment	4,712		4,712		4,712
Furniture and fixtures
Property Plant And Equipment [Line Items]
Property and equipment	1,435		1,435		1,435
Office equipment
Property Plant And Equipment [Line Items]
Property and equipment	621		621		621
Computer equipment
Property Plant And Equipment [Line Items]
Property and equipment	$ 98		$ 98		$ 98