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Segment Reporting (Details)
$ in Thousands
12 Months Ended
Dec. 31, 2024
USD ($)
segment
Dec. 31, 2023
USD ($)
Segment Reporting [Abstract]    
Number of operating segments | segment 1  
Segment Reporting Information [Line Items]    
General and administrative $ 42,124 $ 42,081
Total operating expenses 155,198 159,787
Non-operating income (14,429) (7,818)
Net loss (105,316) (132,493)
Reportable Segment | Operating Segments    
Segment Reporting Information [Line Items]    
Development expenses 59,003 59,297
Research expenses 30,815 38,015
General and administrative 33,281 35,240
Total operating expenses 123,099 132,552
Non-operating income (14,298) (6,538)
Adjustments or reconciling items (3,485) 6,479
Net loss $ (105,316) $ (132,493)