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Income taxes - Schedule of effective income tax rate reconciliation (Details)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Income Tax Disclosure [Abstract]    
Income tax benefit computed at federal statutory tax rate 21.00% 21.00%
State tax—net of federal 6.40% 4.20%
Federal credits 3.00% 3.50%
State credits 1.30% 1.40%
Other permanent differences (1.00%) (0.20%)
Withholding tax 0.00% (0.90%)
Stock-based compensation (4.20%) (2.80%)
Valuation allowance (26.60%) (27.20%)
Total (0.10%) (1.00%)