Accrued expenses and other current liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Payables and Accruals [Abstract]
Accrued research and development	$ 10,064	$ 11,243
Accrued compensation and benefits	7,428	7,344
Other	1,871	2,043
Total accrued expenses and other current liabilities	$ 19,363	20,630
Wind down activities		$ 3,100