Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Income Statement [Abstract]
Revenue from collaboration agreements	$ 35,584	$ 20,756
Operating expenses:
Research and development	110,637	117,706
General and administrative	42,124	42,081
Restructuring	2,437	0
Total operating expenses	155,198	159,787
Loss from operations	(119,614)	(139,031)
Other income (expense), net
Interest expense and amortization of long-term debt—related party	0	(1,373)
Loss on early extinguishment of debt	0	(621)
Interest and other income, net	14,429	9,812
Total other income, net	14,429	7,818
Loss before income taxes	(105,185)	(131,213)
Income tax expense	(131)	(1,280)
Net loss	$ (105,316)	$ (132,493)
Net loss per share — basic (in dollars per share)	$ (1.52)	$ (2.67)
Net loss per share — diluted (in dollars per share)	$ (1.52)	$ (2.67)
Weighted-average number of shares - basic (in shares)	69,372,993	49,640,505
Weighted-average number of shares - diluted (in shares)	69,372,993	49,640,505
Other Comprehensive income (loss):
Unrealized gain on marketable securities	$ 180	$ 4,010
Comprehensive loss	$ (105,136)	$ (128,483)
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]	Collaborative Arrangement [Member]	Collaborative Arrangement [Member]