Property and equipment - Summary of property and equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Property Plant And Equipment [Line Items]
Total property and equipment	$ 15,078	$ 14,895
Less: accumulated depreciation	(9,236)	(7,763)
Total property and equipment, net	5,842	7,132
Laboratory equipment
Property Plant And Equipment [Line Items]
Total property and equipment	8,212	8,042
Leasehold improvements
Property Plant And Equipment [Line Items]
Total property and equipment	4,712	4,712
Furniture and fixtures
Property Plant And Equipment [Line Items]
Total property and equipment	1,435	1,422
Office equipment
Property Plant And Equipment [Line Items]
Total property and equipment	621	621
Computer equipment
Property Plant And Equipment [Line Items]
Total property and equipment	$ 98	$ 98