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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Income Statement [Abstract]        
Revenue from collaboration agreements $ 15,362,000 $ 11,072,000 $ 30,407,000 $ 17,495,000
Operating expenses:        
Research and development 31,838,000 28,347,000 78,124,000 87,315,000
General and administrative 11,768,000 10,533,000 31,751,000 31,784,000
Restructuring 0 0 2,437,000 0
Total operating expenses 43,606,000 38,880,000 112,312,000 119,099,000
Loss from operations (28,244,000) (27,808,000) (81,905,000) (101,604,000)
Other income (expense), net:        
Interest expense and amortization of long-term debt − related party 0 (167,000) 0 (1,373,000)
Loss on early extinguishment of debt 0 (621,000) 0 (621,000)
Interest and other income, net 3,578,000 2,562,000 11,162,000 6,862,000
Total other income, net 3,578,000 1,774,000 11,162,000 4,868,000
Loss before income taxes (24,666,000) (26,034,000) (70,743,000) (96,736,000)
Income tax expense 0 (1,003,000) 0 (1,003,000)
Net loss $ (24,666,000) $ (27,037,000) $ (70,743,000) $ (97,739,000)
Net loss per share − basic (in dollars per share) $ (0.35) $ (0.55) $ (1.03) $ (1.99)
Net loss per share − diluted (in dollars per share) $ (0.35) $ (0.55) $ (1.03) $ (1.99)
Weighted-average number of shares used in computed net loss per share − basic 69,627,190 49,212,126 68,958,938 49,103,351
Weighted-average number of shares used in computed net loss per share − diluted 69,627,190 49,212,126 68,958,938 49,103,351
Other comprehensive income (loss)        
Unrealized gain on marketable securities $ 895,000 $ 870,000 $ 582,000 $ 3,233,000
Comprehensive loss $ (23,771,000) $ (26,167,000) $ (70,161,000) $ (94,506,000)
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]     Collaborative Arrangement [Member] Collaborative Arrangement [Member]