Nature of the business and basis of presentation (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Dec. 31, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Net loss	$ 70,743	$ 97,739
Accumulated deficit	599,126		$ 528,383
Cash, cash equivalents and marketable securities	$ 284,400