Nature of the business and basis of presentation (Details) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Dec. 31, 2023
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Net loss	$ 46,077	$ 70,702
Accumulated deficit	574,460		$ 528,383
Cash, cash equivalents and marketable securities	$ 295,700