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Property and equipment (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Dec. 31, 2023
Property Plant And Equipment [Line Items]      
Property and equipment $ 14,895   $ 14,895
Less: accumulated depreciation (8,139)   (7,763)
Total property and equipment, net 6,756   7,132
Depreciation and amortization expense 448 $ 545  
Laboratory equipment      
Property Plant And Equipment [Line Items]      
Property and equipment 8,042   8,042
Leasehold improvements      
Property Plant And Equipment [Line Items]      
Property and equipment 4,712   4,712
Furniture and fixtures      
Property Plant And Equipment [Line Items]      
Property and equipment 1,422   1,422
Office equipment      
Property Plant And Equipment [Line Items]      
Property and equipment 621   621
Computer equipment      
Property Plant And Equipment [Line Items]      
Property and equipment $ 98   $ 98