Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Income Statement [Abstract]
Revenue from collaboration agreements	$ 20,756	$ 31,096
Operating expenses:
Research and development	117,706	117,841
General and administrative	42,081	42,789
Total operating expenses	159,787	160,630
Loss from operations	(139,031)	(129,534)
Other income (expense), net
Interest expense and amortization of long-term debt—related party	(1,373)	(2,216)
Loss on early extinguishment of debt	(621)	0
Interest and other income, net	9,812	3,575
Total other income (expense), net	7,818	1,359
Loss before income taxes	(131,213)	(128,175)
Income tax expense	(1,280)	0
Net loss	$ (132,493)	$ (128,175)
Net loss per share — basic (in dollars per share)	$ (2.67)	$ (2.62)
Net loss per share — diluted (in dollars per share)	$ (2.67)	$ (2.62)
Weighted-average number of shares - basic (in shares)	49,640,505	48,861,665
Weighted-average number of shares - diluted (in shares)	49,640,505	48,861,665
Other Comprehensive gain (loss):
Unrealized gain (loss) on marketable securities	$ 4,010	$ (3,362)
Comprehensive loss	$ (128,483)	$ (131,537)
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]	Collaborative Arrangement [Member]	Collaborative Arrangement [Member]