Property and equipment - Summary of property and equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2023	Dec. 31, 2022
Property Plant And Equipment [Line Items]
Total property and equipment	$ 14,895	$ 15,523
Less: accumulated depreciation	(7,763)	(8,123)
Total property and equipment, net	7,132	7,400
Laboratory equipment
Property Plant And Equipment [Line Items]
Total property and equipment	8,042	8,757
Leasehold improvements
Property Plant And Equipment [Line Items]
Total property and equipment	4,712	4,682
Furniture and fixtures
Property Plant And Equipment [Line Items]
Total property and equipment	1,422	1,181
Office equipment
Property Plant And Equipment [Line Items]
Total property and equipment	621	529
Computer equipment
Property Plant And Equipment [Line Items]
Total property and equipment	98	191
Construction in progress
Property Plant And Equipment [Line Items]
Total property and equipment	$ 0	$ 183