Nature of the business (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Net loss	$ (132,493)	$ (128,175)
Accumulated deficit	528,383	$ 395,890
Cash, cash equivalents and marketable securities	$ 281,700