Accrued expenses and other current liabilities (Details) - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Accrued expenses and other current liabilities:
Accrued research and development	$ 10,168	$ 9,824
Accrued compensation and benefits	4,235	6,831
Accrued professional fees	870	1,062
Other	1,456	2,052
Total accrued expenses and other current liabilities	$ 16,729	$ 19,769