Collaboration and license agreements - Schedule of financial information related to collaboration and license agreements (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	$ 528	$ 1,473
Deferred revenue, current	14,937	16,618
Deferred revenue, net of current	15,845	16,895
Deferred revenue, total	30,782	33,513
Roche Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	0	417
Deferred revenue, current	5,847	4,649
Deferred revenue, net of current	15,845	16,895
Deferred revenue, total	21,692	21,544
Biogen Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	0	0
Deferred revenue, current	9,090	11,427
Deferred revenue, net of current	0	0
Deferred revenue, total	9,090	11,427
Calico Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	528	1,056
Deferred revenue, current	0	542
Deferred revenue, net of current	0	0
Deferred revenue, total	$ 0	$ 542