Accrued expenses and other current liabilities (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Accrued expenses and other current liabilities:
Accrued research and development	$ 11,154	$ 9,824
Accrued compensation and benefits	2,071	6,831
Accrued professional fees	1,812	1,062
Other	1,258	2,052
Total accrued expenses and other current liabilities	$ 16,295	$ 19,769