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Property and equipment (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Property Plant And Equipment [Line Items]      
Property and equipment $ 16,221   $ 15,523
Less: accumulated depreciation (8,581)   (8,123)
Total property and equipment, net 7,640   7,400
Depreciation and amortization expense 545 $ 305  
Laboratory equipment      
Property Plant And Equipment [Line Items]      
Property and equipment 8,814   8,757
Leasehold improvements      
Property Plant And Equipment [Line Items]      
Property and equipment 4,762   4,682
Furniture and fixtures      
Property Plant And Equipment [Line Items]      
Property and equipment 1,181   1,181
Construction in progress      
Property Plant And Equipment [Line Items]      
Property and equipment 652   183
Office equipment      
Property Plant And Equipment [Line Items]      
Property and equipment 621   529
Computer equipment      
Property Plant And Equipment [Line Items]      
Property and equipment $ 191   $ 191