Marketable securities - Summary of marketable securities in unrealized loss position (Details) $ in Thousands	Mar. 31, 2023 USD ($) security	Dec. 31, 2022 USD ($) security
Number of Securities
Total marketable securities in unrealized loss position, number of securities | security	103	120
Fair Value
Total marketable securities in unrealized loss position	$ 241,492	$ 289,434
Gross Unrealized Losses
Total marketable securities in unrealized loss position	$ (2,481)	$ (4,141)
Corporate debt securities
Number of Securities
Marketable securities in continuous unrealized loss position for less than 12 months, number of securities | security	50	63
Marketable securities in continuous unrealized loss position for greater than 12 months, number of securities | security	37	36
Fair Value
Marketable securities in continuous unrealized loss position for less than 12 months	$ 109,002	$ 134,027
Marketable securities in continuous unrealized loss position for greater than 12 months	74,460	82,375
Gross Unrealized Losses
Marketable securities in continuous unrealized loss position for less than 12 months	(573)	(1,262)
Marketable securities in continuous unrealized loss position for greater than 12 months	$ (910)	$ (1,277)
U.S. government debt securities
Number of Securities
Marketable securities in continuous unrealized loss position for less than 12 months, number of securities | security	3	6
Marketable securities in continuous unrealized loss position for greater than 12 months, number of securities | security	10	7
Fair Value
Marketable securities in continuous unrealized loss position for less than 12 months	$ 6,949	$ 15,748
Marketable securities in continuous unrealized loss position for greater than 12 months	41,132	31,892
Gross Unrealized Losses
Marketable securities in continuous unrealized loss position for less than 12 months	(50)	(245)
Marketable securities in continuous unrealized loss position for greater than 12 months	$ (862)	$ (1,100)
U.S. Treasury securities
Number of Securities
Marketable securities in continuous unrealized loss position for less than 12 months, number of securities | security		4
Marketable securities in continuous unrealized loss position for greater than 12 months, number of securities | security	3	4
Fair Value
Marketable securities in continuous unrealized loss position for less than 12 months		$ 5,575
Marketable securities in continuous unrealized loss position for greater than 12 months	$ 9,949	19,817
Gross Unrealized Losses
Marketable securities in continuous unrealized loss position for less than 12 months		(11)
Marketable securities in continuous unrealized loss position for greater than 12 months	$ (86)	$ (246)