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Loss per share (Tables)
3 Months Ended
Mar. 31, 2023
Earnings Per Share [Abstract]  
Schedule of diluted net loss per share attributable to common stockholders The Company excluded the following potential common shares presented based on amounts outstanding at period end from the computation of diluted net loss per share for the periods indicated because including them would have had an anti-dilutive effect:
 As of March 31,
 20232022
Anti-dilutive common stock equivalents:
Options to purchase common stock8,464,159 7,321,491 
Total anti-dilutive common stock equivalents8,464,159 7,321,491 
Schedule of basic and diluted loss per share
Basic and diluted loss per share is computed by dividing net loss by the weighted-average common shares outstanding for the three months ended March 31, 2023 and 2022 (in thousands, except share and per share data):
Three Months Ended March 31,
20232022
Numerator:
Net loss$(34,780)$(31,620)
Denominator:
Weighted-average number of shares used in computed net loss per share − basic and diluted49,032,319 48,734,827 
Net loss per share − basic and diluted$(0.71)$(0.65)