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Loss per share
3 Months Ended
Mar. 31, 2023
Earnings Per Share [Abstract]  
Loss per share Loss per shareFor periods in which the Company reports a net loss attributable to common stockholders, potentially dilutive securities have been excluded from the computation of diluted net loss per share as their effects would be anti-dilutive. Therefore, the
weighted average number of common shares outstanding used to calculate both basic and diluted net loss per share is the same. For purposes of the dilutive net loss per share calculation, stock options, and restricted stock units for which the performance or market vesting conditions have been met are considered to be common stock equivalents, while restricted stock units with performance or market vesting conditions that were not met as of March 31, 2023 are not considered to be common stock equivalents. The Company excluded the following potential common shares presented based on amounts outstanding at period end from the computation of diluted net loss per share for the periods indicated because including them would have had an anti-dilutive effect:
 As of March 31,
 20232022
Anti-dilutive common stock equivalents:
Options to purchase common stock8,464,159 7,321,491 
Total anti-dilutive common stock equivalents8,464,159 7,321,491 
Basic and diluted loss per share is computed by dividing net loss by the weighted-average common shares outstanding for the three months ended March 31, 2023 and 2022 (in thousands, except share and per share data):
Three Months Ended March 31,
20232022
Numerator:
Net loss$(34,780)$(31,620)
Denominator:
Weighted-average number of shares used in computed net loss per share − basic and diluted49,032,319 48,734,827 
Net loss per share − basic and diluted$(0.71)$(0.65)