Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Cash flows used in operating activities:
Net loss	$ (128,175)	$ (83,892)
Adjustments to reconcile net loss to cash used in operating activities:
Stock-based compensation expense	30,016	21,512
Depreciation and amortization	1,676	1,492
Reduction in carrying amount of right-of-use asset	5,896	1,415
Accretion of discount on marketable securities	714	1,879
Amortization of debt discount—related party	713	719
Changes in operating assets and liabilities:
Accounts receivable	4,244	(1,232)
Prepaid expenses and other current and long-term assets	388	(6,116)
Accounts payable	(3,333)	(1,179)
Accrued expenses and other current liabilities	5,083	4,377
Operating lease liability	(507)	(888)
Deferred revenue	(22,654)	(25,052)
Net cash used in operating activities	(105,939)	(86,965)
Cash flows provided by (used in) investing activities:
Proceeds from maturities of marketable securities	283,445	349,681
Purchase of marketable securities	(219,527)	(537,740)
Purchases of property and equipment	(5,496)	(1,277)
Net cash provided by (used in) investing activities	58,422	(189,336)
Cash flows provided by financing activities:
Proceeds from follow-on offering, net of issuance costs paid of $11.3 million	0	169,465
Proceeds from exercises of stock options	777	2,330
Payment of initial public offering costs	0	(286)
Other	370	(109)
Net cash provided by financing activities	1,147	171,400
Net change in cash, cash equivalents and restricted cash	(46,370)	(104,901)
Cash, cash equivalents and restricted cash at beginning of period	79,403	184,304
Cash, cash equivalents and restricted cash at end of period	33,033	79,403
Reconciliation of cash, cash equivalents and restricted cash:
Cash, cash equivalents and restricted cash at end of year	33,033	79,403
Less: restricted cash	(3,279)	(3,279)
Cash and cash equivalents at end of the year	29,754	76,124
Supplemental disclosure of cash flow information:
Cash paid for interest - related party	1,624	1,308
Supplemental disclosures of non-cash investing and financing activities:
Operating lease liabilities arising from obtaining right-of-use assets	44,067	20,131
Capital expenditures in accounts payable and accrued expenses	473	0
Aggregate exercise price of warrant net exercised - related party (Note 10)	$ 0	$ 3,002