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Income Taxes - Schedule of effective income tax rate reconciliation (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]    
Income tax benefit computed at federal statutory tax rate 21.00% 21.00%
State tax—net of federal 8.00% 6.00%
Federal credits 1.40% 3.10%
State credits 0.10% 1.70%
Other permanent differences (0.80%) (0.30%)
Stock-based compensation (3.00%) (1.30%)
Valuation allowance (26.70%) (30.20%)
Total 0.00% 0.00%