Collaboration and license agreements - Schedule of financial information related to collaboration and license agreements (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	$ 1,473	$ 5,716
Deferred revenue, current	16,618	31,800
Deferred revenue, net of current	16,895	24,368
Deferred Revenue, Total	33,513	56,168
Roche Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	417	1,215
Deferred revenue, current	4,649	5,601
Deferred revenue, net of current	16,895	17,215
Deferred Revenue, Total	21,544	22,816
Biogen Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	0	3,000
Deferred revenue, current	11,427	24,032
Deferred revenue, net of current	0	6,611
Deferred Revenue, Total	11,427	30,643
Calico Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	1,056	1,501
Deferred revenue, current	542	2,167
Deferred revenue, net of current	0	542
Deferred Revenue, Total	$ 542	$ 2,709