Collaboration and license agreements - Allocation of total transaction price and unsatisfied transaction price (Details) $ in Thousands	Dec. 31, 2022 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction Price Allocated	$ 67,822
Transaction Price Unsatisfied	28,044
Research and development targets
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction Price Allocated	61,074
Transaction Price Unsatisfied	25,542
Option rights
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction Price Allocated	6,748
Transaction Price Unsatisfied	$ 2,502