Property and equipment - Summary of property and equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Property Plant And Equipment [Line Items]
Total property and equipment	$ 15,523	$ 10,024
Less: accumulated depreciation	(8,123)	(6,916)
Total property and equipment, net	7,400	3,108
Laboratory equipment
Property Plant And Equipment [Line Items]
Total property and equipment	8,757	8,276
Leasehold improvements
Property Plant And Equipment [Line Items]
Total property and equipment	4,682	541
Furniture and fixtures
Property Plant And Equipment [Line Items]
Total property and equipment	1,181	805
Office equipment
Property Plant And Equipment [Line Items]
Total property and equipment	529	179
Computer equipment
Property Plant And Equipment [Line Items]
Total property and equipment	191	223
Construction in progress
Property Plant And Equipment [Line Items]
Total property and equipment	$ 183	$ 0