Marketable securities - Summary of marketable securities in unrealized loss position (Details) $ in Thousands	Dec. 31, 2022 USD ($) security	Dec. 31, 2021 USD ($) security
Number of Securities
Marketable securities in continuous unrealized loss position for greater than 12 months, Number of securities | security		0
Total marketable securities in unrealized loss position, Number of securities | security	120	123
Fair Value
Total marketable securities in unrealized loss position	$ 289,434	$ 365,505
Gross Unrealized Losses
Total marketable securities in unrealized loss position	$ (4,141)	$ (776)
Corporate debt securities
Number of Securities
Marketable securities in continuous unrealized loss position for less than 12 months, Number of securities | security	63	110
Marketable securities in continuous unrealized loss position for greater than 12 months, Number of securities | security	36
Fair Value
Marketable securities in continuous unrealized loss position for less than 12 months	$ 134,027	$ 303,450
Marketable securities in continuous unrealized loss position for greater than 12 months	82,375
Gross Unrealized Losses
Marketable securities in continuous unrealized loss position for less than 12 months	(1,262)	$ (653)
Marketable securities in continuous unrealized loss position for greater than 12 months	$ (1,277)
U.S. government debt securities
Number of Securities
Marketable securities in continuous unrealized loss position for less than 12 months, Number of securities | security	6	8
Marketable securities in continuous unrealized loss position for greater than 12 months, Number of securities | security	7
Fair Value
Marketable securities in continuous unrealized loss position for less than 12 months	$ 15,748	$ 37,883
Marketable securities in continuous unrealized loss position for greater than 12 months	31,892
Gross Unrealized Losses
Marketable securities in continuous unrealized loss position for less than 12 months	(245)	$ (108)
Marketable securities in continuous unrealized loss position for greater than 12 months	$ (1,100)
U.S. Treasury securities
Number of Securities
Marketable securities in continuous unrealized loss position for less than 12 months, Number of securities | security	4	5
Marketable securities in continuous unrealized loss position for greater than 12 months, Number of securities | security	4
Fair Value
Marketable securities in continuous unrealized loss position for less than 12 months	$ 5,575	$ 24,172
Marketable securities in continuous unrealized loss position for greater than 12 months	19,817
Gross Unrealized Losses
Marketable securities in continuous unrealized loss position for less than 12 months	(11)	$ (15)
Marketable securities in continuous unrealized loss position for greater than 12 months	$ (246)