Summary of significant accounting policies- Summary of property and equipment - useful lives (Details)	12 Months Ended
	Dec. 31, 2022
Laboratory equipment
Property Plant And Equipment [Line Items]
Estimated useful life	5 years
Computer equipment
Property Plant And Equipment [Line Items]
Estimated useful life	3 years
Office equipment, furniture and fixtures
Property Plant And Equipment [Line Items]
Estimated useful life	5 years
Leasehold improvements
Property Plant And Equipment [Line Items]
Property, plant and equipment, useful life	Lesser of useful life or remaining lease term