Nature of the business (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Net loss	$ 128,175	$ 83,892
Accumulated deficit	395,890	$ 267,715
Cash, cash equivalents and marketable securities	$ 337,100