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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows used in operating activities:    
Net loss $ (59,032) $ (43,551)
Adjustments to reconcile net loss to cash used in operating activities:    
Stock-based compensation expense 17,086 9,073
Depreciation expense 740 839
Reduction in carrying amount of right-of-use asset 2,890 647
Accretion of discount on marketable securities 1,082 474
Amortization of debt discount − related party 354 360
Changes in operating assets and liabilities:    
Accounts receivable 4,007 (1,729)
Prepaid expenses and other current and long-term assets 1,722 (1,181)
Accounts payable (564) (1,338)
Accrued expenses and other current liabilities (87) 316
Operating lease liability (983) (508)
Deferred revenue (16,006) (6,338)
Net cash used in operating activities (48,791) (42,936)
Cash flows provided by (used in) investing activities:    
Proceeds from maturities of marketable securities 138,057 209,494
Purchases of marketable securities (108,132) (237,622)
Purchases of property and equipment (701) (1,168)
Net cash provided by (used in) investing activities 29,224 (29,296)
Cash flows provided by financing activities:    
Proceeds from follow-on offering, net of issuance costs paid of $10.8 million (Note 10) 0 169,934
Proceeds from exercises of stock options 519 705
Payment of initial public offering costs 0 (286)
Other 220 (3)
Net cash provided by financing activities 739 170,350
Net change in cash, cash equivalents and restricted cash (18,828) 98,118
Cash, cash equivalents and restricted cash at beginning of period 79,403 184,304
Cash, cash equivalents and restricted cash at end of period 60,575 282,422
Reconciliation of cash, cash equivalents and restricted cash:    
Cash, cash equivalents and restricted cash at end of period 60,575 282,422
Less: restricted cash (3,279) (1,276)
Cash and cash equivalents at end of the period 57,296 281,146
Supplemental disclosures of cash flow information:    
Cash paid for interest − related party 828 707
Supplemental disclosures of non-cash investing and financing activities:    
Operating lease liabilities arising from obtaining right-of-use assets 44,067 0
Capital expenditures in accounts payable and accrued expenses 3,270 0
Follow-on costs in accounts payable and accrued expenses 0 451
Aggregate exercise price of warrant net exercised - related party (Note 10) $ 0 $ 3,002