Collaboration and license agreements - Schedule of financial information related to collaboration and license agreements (Details) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	$ 1,709	$ 5,716
Deferred revenue, current	22,170	31,800
Deferred revenue, net of current	17,991	24,368
Deferred revenue, total	40,161	56,168
Roche Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	500	1,215
Deferred revenue, current	4,153	5,601
Deferred revenue, net of current	17,991	17,215
Deferred revenue, total	22,144	22,816
Biogen Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	0	3,000
Deferred revenue, current	16,392	24,032
Deferred revenue, net of current	0	6,611
Deferred revenue, total	16,392	30,643
Calico Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts Receivable	1,209	1,501
Deferred revenue, current	1,625	2,167
Deferred revenue, net of current	0	542
Deferred revenue, total	$ 1,625	$ 2,709