Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Property and equipment (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
Property and equipment (Details) - USD ($) $ in Thousands	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Property Plant And Equipment [Line Items]
Property and equipment	$ 13,765		$ 13,765		$ 10,024
Less: accumulated depreciation	(7,428)		(7,428)		(6,916)
Total property and equipment, net	6,337		6,337		3,108
Depreciation expense	435	$ 388	740	$ 839
Laboratory equipment
Property Plant And Equipment [Line Items]
Property and equipment	8,200		8,200		8,276
Furniture and fixtures
Property Plant And Equipment [Line Items]
Property and equipment	839		839		805
Leasehold improvements
Property Plant And Equipment [Line Items]
Property and equipment	703		703		541
Office equipment
Property Plant And Equipment [Line Items]
Property and equipment	398		398		179
Computer equipment
Property Plant And Equipment [Line Items]
Property and equipment	255		255		223
Construction in progress
Property Plant And Equipment [Line Items]
Property and equipment	$ 3,370		$ 3,370		$ 0