Nature of the Business and Basis of Presentation - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Net loss	$ 31,620	$ 20,971
Accumulated deficit	299,335		$ 267,715
Cash, cash equivalents and marketable securities	$ 421,700