Entity Central Index Key Lessee operating lease liability payments due after year four. Cover [Abstract] Document Type Document Type Amendment Flag Amendment Flag Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Trading Symbol Trading Symbol Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Current Reporting Status Entity Current Reporting Status Entity Interactive Data Current Entity Interactive Data Current Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Ex Transition Period Entity Ex Transition Period Entity Shell Company Entity Shell Company Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Entity File Number Entity File Number Entity Tax Identification Number Entity Tax Identification Number Entity Address, Address Line One Entity Address Address Line1 Entity Address, Address Line Two Entity Address Address Line2 Entity Address, City or Town Entity Address City Or Town Entity Address, State or Province Entity Address State Or Province Entity Address, Postal Zip Code Entity Address Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Title of 12(b) Security Security12b Title Security Exchange Name Security Exchange Name Entity Incorporation, State or Country Code Entity Incorporation State Country Code Document Quarterly Report Document Quarterly Report Document Transition Report Document Transition Report Statement Of Financial Position [Abstract] Assets Assets [Abstract] Current assets: Assets Current [Abstract] Cash and cash equivalents Cash And Cash Equivalents At Carrying Value Marketable securities, current Marketable Securities Current Accounts receivable Accounts Receivable Net Current Prepaid expenses and other current assets Prepaid Expense And Other Assets Current Total current assets Assets Current Marketable securities, non-current Marketable Securities Noncurrent Property and equipment, net Property Plant And Equipment Net Right-of-use asset Operating Lease Right Of Use Asset Restricted cash Restricted Cash And Cash Equivalents Noncurrent Total assets Assets Liabilities and Stockholders’ Equity Liabilities And Stockholders Equity [Abstract] Current liabilities: Liabilities Current [Abstract] Accounts payable Accounts Payable Current Accrued expenses and other current liabilities Accrued Liabilities And Other Liabilities Deferred revenue, current Deferred Revenue Current Operating lease liability, current Operating Lease Liability Current Total current liabilities Liabilities Current Deferred revenue, net of current Deferred Revenue Noncurrent Operating lease liability, net of current Operating Lease Liability Noncurrent Long-term debt − related party Long Term Debt Noncurrent Total liabilities Liabilities Commitments and contingencies Commitments And Contingencies Stockholders’ equity: Stockholders Equity [Abstract] Preferred stock, par value of $0.0001 per share; 10,000,000 shares authorized, and no shares issued or outstanding as of March 31, 2021 and December 31, 2020, respectively Preferred Stock Value Common stock, par value of $0.0001 per share; 150,000,000 shares authorized, and 43,108,960 and 43,059,632 shares issued and outstanding as of March 31, 2021 and December 31, 2020, respectively Common Stock Value Additional paid-in capital Additional Paid In Capital Common Stock Accumulated other comprehensive (loss) income Accumulated Other Comprehensive Income Loss Net Of Tax Accumulated deficit Retained Earnings Accumulated Deficit Total stockholders’ equity Stockholders Equity Total liabilities and stockholders’ equity Liabilities And Stockholders Equity Preferred stock, par value per share Preferred Stock Par Or Stated Value Per Share Preferred stock, shares authorized Preferred Stock Shares Authorized Preferred stock, shares issued Preferred Stock Shares Issued Preferred stock, shares outstanding Preferred Stock Shares Outstanding Common stock, par value per share Common Stock Par Or Stated Value Per Share Common stock, shares authorized Common Stock Shares Authorized Common stock, shares issued Common Stock Shares Issued Common stock, shares outstanding Common Stock Shares Outstanding Interest expense and amortization of long term debt related party. Income Statement [Abstract] Revenue from collaboration agreements Revenue From Collaborative Arrangement Excluding Revenue From Contract With Customer Operating expenses: Operating Expenses [Abstract] Research and development Research And Development Expense General and administrative General And Administrative Expense Total operating expenses Operating Expenses Loss from operations Operating Income Loss Other (expense) income, net: Nonoperating Income Expense [Abstract] Interest expense and amortization of long-term debt − related party Interest Expense And Amortization Of Long Term Debt Related Party Interest and other income, net Interest And Other Income Total other (expense) income, net Nonoperating Income Expense Loss before income taxes Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest Income tax benefit Income Tax Expense Benefit Net loss Net Income Loss Unrealized loss on marketable securities Marketable Securities Unrealized Gain Loss Comprehensive loss Comprehensive Income Net Of Tax Reconciliation of net loss to net loss attributable to common stockholders: Net Income Loss [Abstract] Net loss Accrual of preferred stock dividends Preferred Stock Dividends Income Statement Impact Net loss attributable to common stockholders Net Income Loss Available To Common Stockholders Basic Net loss per share attributable to common stockholders − basic and diluted Earnings Per Share Basic And Diluted Weighted-average number of shares used in computed net loss per share − basic and diluted Weighted Average Number Of Share Outstanding Basic And Diluted Adjustments to additional paid in capital share based compensation requisite service period recognition, shares. Vested stock option settlement. Statement Of Stockholders Equity [Abstract] Statement [Table] Statement [Table] Equity Components Statement Equity Components [Axis] Equity Component Equity Component [Domain] Accumulated Other Comprehensive Income (Loss) Accumulated Other Comprehensive Income [Member] Common Stock Common Stock [Member] Additional Paid-in Capital Additional Paid In Capital [Member] Accumulated Deficit Retained Earnings [Member] Class of Stock Statement Class Of Stock [Axis] Class of Stock Class Of Stock [Domain] Redeemable Convertible Preferred Stock Redeemable Convertible Preferred Stock [Member] Statement [Line Items] Statement [Line Items] Beginning balance Beginning balance, Shares Shares Outstanding Redeemable convertible preferred stock, Beginning balance, Shares Temporary Equity Shares Outstanding Redeemable convertible preferred stock, Beginning balance Temporary Equity Carrying Amount Attributable To Parent Exercise of stock options Stock Issued During Period Value Stock Options Exercised Exercise of stock options, Shares Stock Issued During Period Shares Stock Options Exercised Stock-based compensation Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Stock-based compensation, Shares Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Shares Repurchase of common stock Stock Repurchased During Period Value Repurchase of common stock, Shares Stock Repurchased During Period Shares Vested stock option settlement Vested Stock Option Settlement Other Adjustments To Additional Paid In Capital Other Ending balance Ending balance, Shares Redeemable convertible preferred stock, Beginning balance, Shares Redeemable convertible preferred stock, Beginning balance Increase decrease in operating lease liability. Stock option repurchases included in accrued expenses. Vested stock option liability included in accrued expenses. Statement Of Cash Flows [Abstract] Cash flows used in operating activities: Net Cash Provided By Used In Operating Activities [Abstract] Net loss Profit Loss Adjustments to reconcile net loss to cash provided by (used in) operating activities: Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Depreciation expense Depreciation Stock-based compensation expense Share Based Compensation Accretion of discount on marketable securities Accretion Amortization Of Discounts And Premiums Investments Reduction in carrying amount of right-of-use assets Operating Lease Right Of Use Asset Amortization Expense Amortization of debt discount Amortization Of Debt Discount Premium Changes in operating assets and liabilities: Increase Decrease In Operating Capital [Abstract] Accounts receivable Increase Decrease In Accounts Receivable Prepaid expenses and other current assets Increase Decrease In Prepaid Deferred Expense And Other Assets Accounts payable Increase Decrease In Accounts Payable Accrued expenses and other current liabilities Increase Decrease In Accrued Liabilities And Other Operating Liabilities Operating lease liability Increase Decrease In Operating Lease Liability Deferred revenue Increase Decrease In Deferred Revenue Net cash used in operating activities Net Cash Provided By Used In Operating Activities Cash flows used in investing activities: Net Cash Provided By Used In Investing Activities [Abstract] Sales and maturities of marketable securities Proceeds From Sale And Maturity Of Marketable Securities Purchases of marketable securities Payments To Acquire Marketable Securities Purchases of property and equipment Payments To Acquire Property Plant And Equipment Net cash used in investing activities Net Cash Provided By Used In Investing Activities Cash flows (used in) provided by financing activities: Net Cash Provided By Used In Financing Activities [Abstract] Proceeds from exercises of stock options Proceeds From Stock Options Exercised Payment of initial public offering costs Payments For Repurchase Of Initial Public Offering Other Proceeds From Payments For Other Financing Activities Net cash (used in) provided by financing activities Net Cash Provided By Used In Financing Activities Net change in cash, cash equivalents and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Excluding Exchange Rate Effect Cash, cash equivalents and restricted cash at beginning of period Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Cash, cash equivalents and restricted cash at end of period Reconciliation of cash, cash equivalents and restricted cash: Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents [Abstract] Less: restricted cash Restricted Cash And Cash Equivalents Cash and cash equivalents at end of the period Supplemental disclosures of cash flow information: Supplemental Cash Flow Information [Abstract] Cash paid for interest Interest Paid Net Supplemental disclosures of non-cash investing and financing activities: Noncash Investing And Financing Items [Abstract] Capital expenditures in accounts payable and accrued expenses Capital Expenditures Incurred But Not Yet Paid Stock option repurchases included in accrued expenses Stock Option Repurchases Included In Accrued Expenses Vested stock option liability included in accrued expenses Vested Stock Option Liability Included In Accrued Expenses Organization Consolidation And Presentation Of Financial Statements [Abstract] Nature of the Business and Basis of Presentation Organization Consolidation And Presentation Of Financial Statements Disclosure [Text Block] Accounting Policies [Abstract] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Fair Value Disclosures [Abstract] Fair Value Measurements Fair Value Disclosures [Text Block] Marketable Securities [Abstract] Marketable Securities Investments In Debt And Marketable Equity Securities And Certain Trading Assets Disclosure [Text Block] Property Plant And Equipment [Abstract] Property and Equipment Property Plant And Equipment Disclosure [Text Block] Leases [Abstract] Leases Lessee Operating Leases [Text Block] Payables And Accruals [Abstract] Accrued Expenses and Other Current Liabilities Accounts Payable Accrued Liabilities And Other Liabilities Disclosure Current [Text Block] Collaboration and license agreements. Collaboration And License Agreements [Abstract] Collaboration and License Agreements Collaborative Arrangement Disclosure [Text Block] Long term debt and warrant related party. Long term debt and warrant related party. Long Term Debt And Warrant Related Party [Abstract] Long Term Debt and Warrant - Related Party Long Term Debt And Warrant Related Party [Text Block] Equity [Abstract] Stockholder's Equity Stockholders Equity Note Disclosure [Text Block] Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Stock-based Compensation Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Earnings Per Share [Abstract] Loss Per Share Earnings Per Share [Text Block] Basis of presentation and consolidation. Basis of Presentation and Consolidation Basis Of Presentation And Consolidation Policy [Text Block] Marketable Securities Marketable Securities Policy Unaudited interim financial information. Unaudited Interim Financial Information Unaudited Interim Financial Information Policy [Text Block] Significant Accounting Policies Basis Of Accounting Policy Policy [Text Block] Use of Estimates Use Of Estimates Recently Issued Accounting Standards New Accounting Pronouncements Policy Policy [Text Block] Schedule of Financial Assets Measured at Fair Value on Recurring Basis Schedule Of Fair Value Assets And Liabilities Measured On Recurring Basis Table [Text Block] Summary of Marketable Securities Marketable Securities [Text Block] Summary of Property and Equipment Property Plant And Equipment [Text Block] Schedule of depreciation expense. Summary of Depreciation Expense Related to Property and Equipment Schedule Of Depreciation Expense Table [Text Block] Lessee Lease Description [Table] Lessee Lease Description [Table] Lease Contractual Term Lease Contractual Term [Axis] Lease Contractual Term Lease Contractual Term [Domain] Watertown lease. Watertown Lease Watertown Lease [Member] Lessee Lease Description [Line Items] Lessee Lease Description [Line Items] Summary of Lease Costs Lease Cost Table [Text Block] Tabular disclosure of lease term and discount rate applied in arriving at lease liability. Summary of Lease Term and Discount Rate Applied in Arriving at Lease Liability Summarizes Lease Term And Discount Rate Applied In Arriving At Lease Liability Table [Text Block] Undiscounted Minimum Future Lease Payments Under Non-cancelable Leases Lessee Operating Lease Liability Maturity Table [Text Block] Summary of Accrued Expenses and Other Current Liabilities Schedule Of Accrued Liabilities Table [Text Block] Revenue from collaboration agreements. Schedule of Revenue from Collaboration Agreements Revenue From Collaboration Agreements Table [Text Block] Financial information related to the collaboration and license agreements. Schedule of Financial Information Related to Collaboration and License Agreements Financial Information Related To Collaboration And License Agreements Table [Text Block] Supplemental financial information related to collaboration and license agreements. Schedule of Supplemental Financial Information Related to Collaboration and License Agreements Supplemental Financial Information Related To Collaboration And License Agreements Table [Text Block] Summary of Anticipated Future Minimum Payments of Long-term Debt Schedule Of Maturities Of Long Term Debt Table [Text Block] Schedule of Stock-based Compensation Expense Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Summary of Stock Option Activity Schedule Of Share Based Compensation Stock Options Activity Table [Text Block] Schedule of Computation of Diluted Net Loss Per Share Attributable to Common Stockholders Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Schedule of Basic and Diluted Loss Per Share Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Schedule Of Stock By Class [Table] Schedule Of Stock By Class [Table] Sale of Stock Subsidiary Sale Of Stock [Axis] Sale of Stock Sale Of Stock Name Of Transaction [Domain] IPO I P O [Member] Class Of Stock [Line Items] Class Of Stock [Line Items] Net loss Accumulated deficit Initial public offering closing date. Net proceeds after deducting underwriting discounts, commissions and expenses. Initial public offering closing date Initial Public Offering Closing Date Issued shares of common stock Stock Issued During Period Shares New Issues Shares issued price per share Shares Issued Price Per Share Net proceeds after deducting underwriting discounts, commissions and expenses Net Proceeds After Deducting Underwriting Discounts Commissions And Expenses Outstanding shares of preferred stock automatically converted Convertible Preferred Stock Shares Issued Upon Conversion Cash, cash equivalents and marketable securities Cash Cash Equivalents And Short Term Investments Reverse stock split Stockholders Equity Reverse Stock Split Stock split conversion ratio Stockholders Equity Note Stock Split Conversion Ratio1 Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Abstract] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Cash and Cash Equivalents Cash And Cash Equivalents [Axis] Cash and Cash Equivalents Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member] Money Market Funds Money Market Funds [Member] Corporate Debt Securities Corporate Debt Securities [Member] US Treasury Securities U S Treasury Securities [Member] U.S. Government Debt Securities U S States And Political Subdivisions [Member] Fair Value Hierarchy and NAV Fair Value By Fair Value Hierarchy Level [Axis] Fair Value Hierarchy and NAV Fair Value Measurements Fair Value Hierarchy [Domain] Level 1 Fair Value Inputs Level1 [Member] Level 2 Fair Value Inputs Level2 [Member] Level 3 Fair Value Inputs Level3 [Member] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Cash equivalents: Cash And Cash Equivalents [Abstract] Money market funds Cash And Cash Equivalents Fair Value Disclosure Marketable securities: Corporate debt securities Investments Fair Value Disclosure Total cash equivalents and marketable securities Assets Fair Value Disclosure Fair value assets level 1 to level 3 transfers amount. Fair value assets level 3 to level 1 transfers amount. Fair value liabilities level 1 to level 3 transfers amount. Fair value liabilities level 3 to level 1 transfers amount. Fair value assets level 2 to level 3 transfers amount. Fair value assets level 3 to level 2 transfers amount. Fair value liabilities level 2 to level 3 transfers amount. Fair value liabilities level 3 to level 2 transfers amount. Fair value, assets, level 1 to level 2 transfers, amount Fair Value Assets Level1 To Level2 Transfers Amount Fair value, assets, level 2 to level 1 transfers, amount Fair Value Assets Level2 To Level1 Transfers Amount Fair value, liabilities, level 1 to level 2 transfers, amount Fair Value Liabilities Level1 To Level2 Transfers Amount Fair value, liabilities, level 2 to level 1 transfers, amount Fair Value Liabilities Level2 To Level1 Transfers Amount Fair value, assets, level 1 to level 3 transfers, amount Fair Value Assets Level1 To Level3 Transfers Amount Fair value, assets, level 3 to level 1 transfers, amount Fair Value Assets Level3 To Level1 Transfers Amount Fair value, liabilities, level 1 to level 3 transfers, amount Fair Value Liabilities Level1 To Level3 Transfers Amount Fair value, liabilities, level 3 to level 1 transfers, amount Fair Value Liabilities Level3 To Level1 Transfers Amount Fair value, assets, level 2 to level 3 transfers, amount Fair Value Assets Level2 To Level3 Transfers Amount Fair value, assets, level 3 to level 2 transfers, amount Fair Value Assets Level3 To Level2 Transfers Amount Fair value, liabilities, level 2 to level 3 transfers, amount Fair Value Liabilities Level2 To Level3 Transfers Amount Fair value, liabilities, level 3 to level 2 transfers, amount Fair Value Liabilities Level3 To Level2 Transfers Amount Schedule Of Available For Sale Securities [Table] Schedule Of Available For Sale Securities [Table] Investment Type Investment Type [Axis] Investments Investment Type Categorization [Member] U.S. Government Debt Securities U S Government Debt Securities [Member] Schedule Of Available For Sale Securities [Line Items] Schedule Of Available For Sale Securities [Line Items] Amortized Cost Available For Sale Debt Securities Amortized Cost Basis Gross Unrealized Gains Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax Gross Unrealized Losses Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax Fair Value Available For Sale Securities Debt Securities Number of marketable securities. Individual securities. Number of marketable securities Number Of Marketable Securities Marketable securities Marketable Securities Individual securities Individual Securities Other-than-temporary impairment losses Impairment Of Investments Schedule Of Property Plant And Equipment [Table] Schedule Of Property Plant And Equipment [Table] Long-Lived Tangible Asset Property Plant And Equipment By Type [Axis] Long-Lived Tangible Asset Property Plant And Equipment Type [Domain] Laboratory equipment. Laboratory Equipment Laboratory Equipment [Member] Furniture and Fixtures Furniture And Fixtures [Member] Leasehold Improvements Leaseholds And Leasehold Improvements [Member] Computer Equipment Computer Equipment [Member] Office Equipment Office Equipment [Member] Property Plant And Equipment [Line Items] Property Plant And Equipment [Line Items] Property and equipment, gross Property Plant And Equipment Gross Less: accumulated depreciation Accumulated Depreciation Depletion And Amortization Property Plant And Equipment Total property and equipment, net Lease collateral amount. Lessee operating lease commencement date. Rent commencing date. Lease non-cancelable term. Balance Sheet Location Balance Sheet Location [Axis] Balance Sheet Location Balance Sheet Location [Domain] Restricted cash. Restricted Cash Restricted Cash [Member] Lessee operating lease, description Lessee Operating Lease Description Lease commencement date Lessee Operating Lease Commencement Date Rent commencing date Rent Commencing Date Lease non-cancelable term Lease Non Cancelable Term Lease collateral amount Lease Collateral Amount Lease costs. Lease costs table. Lease Costs [Table] Lease Costs [Table] Lease Costs [Line Items] Lease Costs [Line Items] Lease cost: Lease Cost [Abstract] Operating lease cost Operating Lease Cost Variable lease cost Variable Lease Cost Total lease cost Lease Cost Remaining lease term Operating Lease Weighted Average Remaining Lease Term1 Discount rate Operating Lease Weighted Average Discount Rate Percent Operating Lease Liabilities Payments Due [Abstract] Remaining 2021 Lessee Operating Lease Liability Payments Remainder Of Fiscal Year 2022 Lessee Operating Lease Liability Payments Due Next Twelve Months 2023 Lessee Operating Lease Liability Payments Due Year Two 2024 Lessee Operating Lease Liability Payments Due Year Three 2025 Lessee Operating Lease Liability Payments Due Year Four Thereafter Lessee Operating Lease Liability Payments Due After Year Four Total undiscounted lease payments Lessee Operating Lease Liability Payments Due Less: imputed interest Lessee Operating Lease Liability Undiscounted Excess Amount Total operating lease liability Operating Lease Liability Accrued research and development, current. Accrued expenses and other current liabilities: Accrued Liabilities And Other Liabilities [Abstract] Accrued research and development Accrued Research And Development Current Accrued compensation and benefits Accrued Employee Benefits Current Accrued professional fees Accrued Professional Fees Current Other Other Liabilities Current Total accrued expenses and other current liabilities Number of potential targets. Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Collaborative Arrangement and Arrangement Other than Collaborative Type Of Arrangement [Axis] Collaborative Arrangement and Arrangement Other than Collaborative Arrangements And Nonarrangement Transactions [Member] Restated Roche agreement. Restated Roche Agreement Restated Roche Agreement [Member] Statistical Measurement Range [Axis] Statistical Measurement Range [Member] Maximum Maximum [Member] Minimum Minimum [Member] Product and Service Product Or Service [Axis] Product and Service Products And Services [Domain] Lead series identification achievement. Lead Series Identification Achievement Lead Series Identification Achievement [Member] Good laboratory practice (“GLP”) toxicology (“Tox”) study phase. Good Laboratory Practice (“GLP”) Toxicology (“Tox”) Study Phase Good Laboratory Practice Glp Toxicology Tox Study Phase [Member] Research and Development Arrangement, Contract to Perform for Others, Type Research And Development Arrangement Contract To Perform For Others By Type [Axis] Research and Development Arrangement, Contract to Perform for Others, Type Research And Development Arrangement Contract To Perform For Others Type [Domain] Research, development and commercial milestone payments. Research, Development and Commercial Milestone Payments Research Development And Commercial Milestone Payments [Member] One-time sales-based payments. One-Time Sales-Based Payments One Time Sales Based Payments [Member] Biogen license agreement Biogen License Agreement Biogen License Agreement [Member] Research and development milestones. Research And Development Milestones Research And Development Milestones [Member] Scenario Statement Scenario [Axis] Scenario Scenario Unspecified [Domain] Scenario Forecast Scenario Forecast [Member] Calico license agreement. Calico License Agreement Calico License Agreement [Member] Potential research, development and commercial milestone payments. Potential Research, Development and Commercial Milestone Payments Potential Research Development And Commercial Milestone Payments [Member] Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Number of potential targets Number Of Potential Targets Upfront fees. Additional upfront consideration. Annual research plan payments receivables. Option exercise fee. Annual research plan payments periods. Additional upfront consideration received Additional Upfront Consideration Annual research plan payments receivables Annual Research Plan Payments Receivables Annual research plan payments periods Annual Research Plan Payments Periods Upfront fees Upfront Fees Option exercise fees Option Exercise Fee Amount eligible to receive Contracts Receivable Claims And Uncertain Amounts Collaboration description. Collaboration description Collaboration Description Agreement date. Number of targeted protein degradation. Research and development agreement period. Additional payment on extension of contract. Additional targets for development. Agreement date Agreement Date Number of targeted protein degradation Number Of Targeted Protein Degradation Research agreement, period Research And Development Agreement Period Additional payment on extension of contract Additional Payment On Extension Of Contract Additional targets for development Additional Targets For Development Non refundable upfront payment. Nonrefundable upfront payment Non Refundable Upfront Payment Payment received Proceeds From Collaborators Notice period for termination of agreement. Written notice period for termination of agreement Notice Period For Termination Of Agreement Number of targets. Number of performance obligation. Number of performance obligation Number Of Performance Obligation Number of targets Number Of Targets Number of additional targets. Number of additional targets Number Of Additional Targets Lead initiation fee achieved. Lead initiation fee achieved Lead Initiation Fee Achieved Research term. Research term Research Term Number of target proteins. Number of target proteins Number Of Target Proteins Upfront payment. Annual payments. Upfront payment Upfront Payment Annual Payments Annual Payments Contractual term. Contractual term Contractual Term Milestone payment received. Milestone payment received Milestone Payment Received Roche agreement. Roche Agreement Roche Agreement [Member] Biogen agreement. Biogen Agreement Biogen Agreement [Member] Calico agreement. Calico Agreement Calico Agreement [Member] Accounts Receivable Receivables Net Current Deferred Revenue, Current Deferred Revenue, Net of Current Deferred Revenue, Total Deferred Revenue Transaction price allocated to performance obligation. Revenue recognized that was included in the contract liability at the beginning of the period Contract With Customer Liability Revenue Recognized Revenue recognized from performance obligations fully or partially satisfied in previous periods Contract With Customer Performance Obligation Satisfied In Previous Period Aggregate amount of the transaction price allocated to the performance obligations that are partially or fully unsatisfied as of the end of the reporting period Transaction Price Allocated To Performance Obligation Cash balance to be maintained in bank account while debt is outstanding. Long-term debt and warrant liability abstract. Long Term Debt And Warrant Liability [Abstract] Long Term Debt And Warrant Liability Related Party. Long-term debt and warrant liability table. Long Term Debt And Warrant Liability [Table] Long Term Debt And Warrant Liability [Table] Credit Facility Credit Facility [Axis] Credit Facility Credit Facility [Domain] Credit agreement with Perceptive Life Sciences Master Fund LTD. Credit Agreement with Perceptive Life Sciences Master Fund LTD Credit Agreement With Perceptive Life Sciences Master Fund L T D [Member] Debt Instrument Debt Instrument [Axis] Debt Instrument, Name Debt Instrument Name [Domain] Term loan. Term Loan Term Loan [Member] Long-term Debt, Type Longterm Debt Type [Axis] Long-term Debt, Type Longterm Debt Type [Domain] Tranche one. Tranche One Tranche One [Member] Tranche two. Tranche Two Tranche Two [Member] Long Term Debt And Warrant Liability Related Party [Line Items] Long Term Debt And Warrant Liability Related Party [Line Items] Amount withdrawn Line Of Credit Description of Variable Rate Basis Debt Instrument Description Of Variable Rate Basis Applicable margin rate Debt Instrument Basis Spread On Variable Rate1 Balance to be maintained in bank account while debt is outstanding Cash Balance To Be Maintained In Bank Account While Debt Is Outstanding Debt instrument. percentage of principal payment until maturity. Date until which interest only payments are made. Date until which interest only payments are made Date Until Which Interest Only Payments Are Made Maturity date Debt Instrument Maturity Date Percentage of principal payments until maturity Debt Instrument Percentage Of Principal Payment Until Maturity Prepayment fee Payments Of Debt Extinguishment Costs Warrant issued to purchase shares Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights Exercise price per share Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1 Long Term Debt By Maturity [Abstract] Remaining 2021 Long Term Debt Maturities Repayments Of Principal Remainder Of Fiscal Year 2022 Long Term Debt Maturities Repayments Of Principal In Next Twelve Months 2023 Long Term Debt Maturities Repayments Of Principal In Year Two 2024 Long Term Debt Maturities Repayments Of Principal In Year Three Total undiscounted, minimum long-term debt payments Debt Instrument Carrying Amount Less: Unamortized debt issuance costs, and debt discount related to warrant Debt Instrument Unamortized Discount Premium And Debt Issuance Costs Net Total long-term debt—related party Long Term Debt Stockholders equity. Stockholders equity. Stockholders Equity [Table] Stockholders Equity [Table] Related Party Related Party Transactions By Related Party [Axis] Related Party Related Party [Domain] Underwriters. Underwriters for IPO Exercised in full Overallotment Option Underwriters [Member] Stockholders Equity [Line Items] Stockholders Equity [Line Items] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Plan Name Plan Name [Axis] Plan Name Plan Name [Domain] 2015 incentive stock option and grant plan. 2015 Incentive Stock Option and Grant Plan Two Thousand Fifteen Incentive Stock Option And Grant Plan [Member] 2020 stock option and incentive plan. 2020 Stock Option and Incentive Plan Two Thousand And Twenty Stock Option And Incentive Plan [Member] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Stock-based compensation, common stock shares reserved for issuance Common Stock Capital Shares Reserved For Future Issuance Stock-based compensation, common stock shares available for issuance Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Payments for relinquishment of right to purchase common stock upon exercise of stock options. Payments for repurchase of common stock Payments For Repurchase Of Common Stock Payments for relinquishment of right to purchase common stock upon exercise of stock options Payments For Relinquishment Of Right To Purchase Common Stock Upon Exercise Of Stock Options Compensation Related Costs [Abstract] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Income Statement Location Income Statement Location [Axis] Income Statement Location Income Statement Location [Domain] Research and Development Research And Development Expense [Member] General and Administrative General And Administrative Expense [Member] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Total stock-based compensation expense Allocated Share Based Compensation Expense Number of stock options, Outstanding as of December 31, 2020 Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Number of stock options, Granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Number of stock options, Exercised Number of stock options, Cancelled or forfeited Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period Number of stock options, Outstanding as of March 31, 2021 Number of stock options, Options exercisable as of March 31,2021 Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number Number of stock options, Vested and expected to vest as of March 31, 2021 Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number Weighted-average exercise price, Outstanding as of December 31, 2020 Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Weighted-average exercise price, Granted Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Weighted-average exercise price, Exercised Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price Weighted-average exercise price, Cancelled or forfeited Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price Weighted-average exercise price, Outstanding as of March 31, 2021 Weighted-average exercise price, Options exercisable as of March 31, 2021 Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Weighted-average exercise price, Vested and expected to vest as of March 31, 2021 Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price Unrecognized compensation costs Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Expected to be recognized over a weighted average period Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1 Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Securities Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities, Name Antidilutive Securities Name [Domain] Options to purchase common stock. Options to Purchase Common Stock Options To Purchase Common Stock [Member] Warrant to purchase common stock. Warrant to Purchase Common Stock Warrant To Purchase Common Stock [Member] Series seed redeemable convertible preferred stock. Series Seed Preferred Stock Series Seed Redeemable Convertible Preferred Stock [Member] Series A Preferred Stock Series A Preferred Stock [Member] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Total anti-dilutive common stock equivalents Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Stock split conversion ratio Numerator: Net Income Loss Available To Common Stockholders Basic [Abstract] Denominator: Weighted Average Number Of Shares Outstanding [Abstract] Net loss per share attributable to common stockholders − basic and diluted Earnings Per Share Basic