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Collaboration and License Agreements - Additional Information (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Dec. 22, 2018
USD ($)
Target
Apr. 30, 2019
USD ($)
Dec. 31, 2018
USD ($)
Protein
Target
Mar. 31, 2016
USD ($)
Protein
Reimbursement
Sep. 30, 2020
USD ($)
Target
Exchange
Performanceobligation
TargetProtein
Sep. 30, 2019
USD ($)
Sep. 30, 2020
USD ($)
Target
Exchange
MaterialRight
Performanceobligation
TargetProtein
Sep. 30, 2019
USD ($)
Jun. 30, 2020
USD ($)
Original Roche Agreement                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Upfront payment             $ 40,000,000    
Expected research plan funding payments             13,500,000    
Remaining deferred revenue         $ 6,400,000   $ 6,400,000    
Original Roche Agreement | Roche JRC | Research and Development License                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Nonrefundable upfront payment and additional fees       $ 15,000,000          
Estimated period to perform research and development       42 months          
Original Roche Agreement | Roche JRC | Research, Development and Commercial Milestone Payments | Research and Development License                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Amount eligible to receive       $ 277,000,000          
Original Roche Agreement | Maximum | Roche                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of targeted protein degradation | Protein       10          
Original Roche Agreement | Maximum | Roche JRC | Research and Development License                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of reimbursements in full-time equivalents | Reimbursement       5          
Original Roche Agreement | Maximum | Roche JRC | One-Time Sales-Based Payments | Research and Development License                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Amount eligible to receive       $ 150,000,000          
Restated Roche Agreement                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of potential targets | Target 6       6   6    
Number of target nominated as of the execution of the Restated Roche Agreement | Target 3                
Number of target not nominated as of the execution of the Restated Roche Agreement | Target 3                
Additional upfront consideration received $ 40,000,000                
Annual research plan payments receivables 1,000,000                
Collaboration description             The Company has control over the committee and may terminate the Restated Roche Agreement on a target-by-target or product-by-product basis under several scenarios, upon at least 90 days’ prior written notice.    
Number of initial targets | Target         3   3    
Number of additional targets | Target             3    
Number of targets | Target         6   6    
Number of exchanges | Exchange         6   6    
Number of additional targets | Target         3   3    
Number of performance obligation | Performanceobligation         12   12    
Restated Roche Agreement | Lead Series Identification Achievement                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Upfront fees 2,000,000                
Restated Roche Agreement | Good Laboratory Practice (“GLP”) Toxicology (“Tox”) Study Phase                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Upfront fees 3,000,000                
Restated Roche Agreement | Progressed Through Clinical Trials                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Option exercise fees 20,000,000                
Restated Roche Agreement | Option to License                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of material rights | MaterialRight             3    
Restated Roche Agreement | Option to Initiate Research Plan                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of additional targets | Target             3    
Number of material rights | MaterialRight             3    
Restated Roche Agreement | Research Services Performance Obligations                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of performance obligation | Performanceobligation         3   3    
Restated Roche Agreement | Commercial License for Six Targets                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of targets | Target         6   6    
Number of performance obligation | Performanceobligation         6   6    
Restated Roche Agreement | Research Services for Uninitiated Three Targets                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of targets | Target         3   3    
Number of performance obligation | Performanceobligation         3   3    
Restated Roche Agreement | Maximum | Research, Development and Commercial Milestone Payments                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Amount eligible to receive 275,000,000                
Restated Roche Agreement | Maximum | One-Time Sales-Based Payments                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Amount eligible to receive 150,000,000                
Restated Roche Agreement | Maximum | Progressed Through Clinical Trials                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Option exercise fees 12,000,000                
Restated Roche Agreement | Minimum | Progressed Through Clinical Trials                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Option exercise fees $ 7,000,000                
Restated Roche Agreement Accounting                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Upfront payment             $ 40,000,000    
Expected research plan funding payments             13,500,000    
Remaining deferred revenue         $ 6,400,000   6,400,000    
Amount of expected research plan funding payments of per active target per year             1,000,000    
Restated Roche Agreement Accounting | Target Two                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Milestone payment received   $ 2,000,000              
Transaction price allocated to performance obligations         61,900,000   $ 61,900,000    
Restated Roche Agreement Accounting | Targets 3                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of material rights | MaterialRight             3    
Transaction price allocated to performance obligations         4,700,000   $ 4,700,000    
Restated Roche Agreement Accounting | Targets 4-6                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Transaction price allocated to performance obligations         28,600,000   28,600,000    
Restated Roche Agreement Accounting | Targets 1-3                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Transaction price allocated to performance obligations         $ 28,600,000   28,600,000    
Restated Roche Agreement Accounting | Maximum                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Amount of expected research plan funding payments of per target             $ 3,000,000    
Biogen License Agreement                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of additional targets | Target             2    
Number of targets | Target         5   5    
Number of performance obligation | Performanceobligation         1   1    
Agreement date     2018-12            
Research agreement, period     54 months       54 months    
Additional payment on extension of contract     $ 62,500,000            
Nonrefundable upfront payment             $ 45,000,000    
Written notice period for termination of agreement             90 days    
Revenue recognized         $ 600,000 $ 200,000 $ 2,000,000 $ 200,000  
Biogen License Agreement | Accounts Receivable and Deferred Revenue                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Milestone payment                 $ 4,000,000
Biogen License Agreement | Maximum                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of targeted protein degradation | Protein     5            
Additional targets for development | Target     5            
Biogen License Agreement | Maximum | One-Time Sales-Based Payments                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Payment received             26,000,000    
Biogen License Agreement | Maximum | Research And Development Milestones                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Payment received             $ 35,000,000    
Biogen License Agreement | Minimum                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Written notice period for termination of agreement             90 days    
Calico License Agreement                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Upfront payment             $ 5,000,000    
Number of targets | Target         5   5    
Number of performance obligation | Performanceobligation         1   1    
Research term               5 years  
Annual Payments             $ 5,000,000    
Contractual term             5 years    
Calico License Agreement | Maximum                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Number of target proteins | TargetProtein         5   5    
Calico License Agreement | Maximum | One-Time Sales-Based Payments                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Payment received             $ 65,000,000    
Calico License Agreement | Maximum | Potential Research, Development and Commercial Milestone Payments                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Payment received             $ 132,000,000