X0206 3 2020-10-01 0 0001662579 C4 Therapeutics, Inc. CCCC 0001132946 COHEN ALAIN J C/O C4 THERAPEUTICS, INC. 490 ARSENAL WAY, SUITE 200 WATERTOWN MA 02472 1 0 1 0 Series Seed Preferred Stock Common Stock 237149 I See Footnote Series A Preferred Stock Common Stock 1482183 I See Footnote Series B Preferred Stock Common Stock 2484425 I By Cobro Ventures Opportunity Fund, L.P. Stock Option (Right to Buy) 2.11 2026-07-12 Common Stock 8561 D Each share of Series Seed Preferred Stock, Series A Preferred Stock, and Series B Preferred Stock is convertible into Common Stock on a 8.4335-to-one basis into the number of shares of Common Stock shown in Column 3 at any time at the holder's election, and automatically upon the closing of the Issuer's initial public offering ("IPO") without payment or further consideration. The shares have no expiration date. Shares held by the Reporting Person as trustee of the Alain J. Cohen Revocable Trust. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. Shares held by Cobro Ventures Opportunity Fund, L.P. ("Cobro Ventures"). The Reporting Person serves as a manager of Cobro Opportunity Fund GP, LLC, the general partner of Cobro Ventures, and may be deemed to exercise voting and investment power over the shares held by Cobro Ventures. The Reporting Person disclaims beneficial ownership of the shares held by Cobro Ventures except to the extent of his pecuniary interest therein. 12.5% of this option vested and became exercisable on December 31, 2016, with the remainder vesting in 28 equal quarterly installments thereafter, subject to the Reporting Person's continuous service through each such date. Exhibit 24 - Power of Attorney /s/ Jolie M. Siegel, Attorney-in-Fact 2020-10-01